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Wednesday, August 11, 2021

What really happened in US’ UNC labs, US Army Fort Detrick, with records of ‘lab-created coronaviruses’ incidents, supervision loopholes and audacious germ researchers ?

Photo: VCG

 

 

Alongside the infamous Fort Detrick lab, a biological laboratory at the University of North Carolina (UNC) at Chapel Hill, led by well-known US coronavirus expert Ralph Baric, has become the focus of public suspicion in the search for the origins of COVID-19, with many observers pointing to its poor safety record and unwillingness of researchers to speak publicly.

` Ralph Baric’s team is the authority when it comes to [coronavirus] research, with widely recognized capability in synergizing and modifying coronaviruses, said Chinese Foreign Ministry spokesperson Zhao Lijian, urging the US to invite World Health Organization (WHO) experts to investigate the UNC facility. “A probe into Baric's team and lab would clarify whether coronavirus research has created or will create SARS-CoV-2,” Zhao said during a press conference in late July.

` The international community clearly views the US, which has been hyping up the “lab-leak theory” and engaging in groundless attacks against China, as a major suspect responsible for leaking COVID-19, one insider told the Global Times.

` With a more [mature] environment of lab virus synthesizing and operating, as well as virus leakage cases in history, the COVID-19 was obviously more likely leaked from the US labs if the lab-leak claim is true, said a Chinese biosecurity specialist surnamed Li (pseudonym), who works at a research institute affiliated with the Chinese Academy of Sciences.

` “We appeal to the WHO to put US labs, including the one located at UNC, into its second phase investigation,” Li told the Global Times.

` Frequent lab-created accidents

` Similar to the Fort Detrick lab, the public has found that high-security labs at UNC have developed a reputation for their frequent accidents, attributed to lax safety procedures. The lab at UNC-Chapel Hill reported 28 lab incidents involving genetically engineered organisms to officials at the US National Institutes of Health (NIH) from January 2016 to June 2020, according to ProPublica, a nonprofit news website based in New York City.

` Six of the incidents involved “various types of lab-created coronaviruses,” according to an article published by ProPublica on August 2020. “Many were engineered to allow the study of the virus in mice,” it added.

` The six coronavirus-related accidents reported by UNC were filled with basic errors and incorrect remedial measures, the Global Times found.

` In August 2015, for instance, a mouse that had been infected with an undisclosed type of “mouse adapted” virus squirmed free of a researcher’s gloved hand and onto the lab floor. NIH officials told ProPublica it was a type of “SARS-associated coronavirus.” Workers involved in the incident were asked to report their temperatures and any symptoms for 10 consecutive days.

` In April 2020, a mouse flipped over in a researcher’s hand and bit an index finger through two layers of gloves. The mouse bite caused potential exposure to a strain of SARS-CoV-2, which had been adapted for growth in mice, the UNC report said. Nonetheless, instead of being placed into medical quarantine, the researcher only undertook 14 days of self-isolation at home.

` It was more likely that UNC labs inadvertently leaked virus through the accidents which infected humans, although the possibility was theoretically small, Li said.

` “A single incident like the UNC reported could hardly cause immediate virus evolution or wide spread,” Li told the Global Times, “but there is possibility that the leakage has led to a modified virus spread among humans – potential up to several hundred of people – through a period of time, and that the virus evolves during human-to-human or human-to-animal transmissions.”

` University of North Carolina (UNC) at Chapel Hil Photo: VCG
` University of North Carolina (UNC) at Chapel Hil Photo: VCG

` Opaque US biosecurity system

` UNC lab accidents are only a tip of the iceberg when it comes to the US’ porous biological labs system. In 2015, a USA Today investigation revealed “hundreds of lab mistakes safety violations and near-miss incidents” that have occurred in biological laboratories coast to coast in recent years, which put “scientists, their colleagues and sometimes even the public at risk.”

` Several Chinese virologists and biologists who had dealt with their US peers shared their concerns over the US’ non-transparent biosecurity system, which, as was noted by many, lacked adequate information reporting and supervision mechanisms.


` Some US labs preserve samples of the viruses they uncover instead of reporting them, said Yang Zhanqiu, a virologist at Wuhan University. “Some samples are even held for decades,” Yang told the Global Times.

` The lack of bottom-up messaging is also a big problem, noted Li. Usually front-line labs carrying out confidential or sophisticated biotechnology projects won’t be punished if they don’t report, or only report part of the whole story with upper-level acquiescence or ignorance, Li said. “That’s why the US government or even the president occasionally just say ‘I don’t know’ in responding to media and the public’s enquiries – they indeed don’t know what is exactly going on [at front-line labs],” he added.

` For the six coronavirus-related incidents at UNC labs, the university declined to answer questions about the incidents or disclose key details to the public, including the names of viruses involved, the nature of the modifications made to them, and what risks were posed to the public, ProPublic said, noting this was “contrary to NIH guidelines.”

` UNC has seemingly paid no price for its reticence. Numerous similar cases have exposed supervision loopholes in biosecurity system, some insiders have noted, warning that it may lead to a few US individual researchers or labs “do whatever they want.”

` At University of Iowa, scientist Stanley Perlman launched work for the deadly MERS virus without faculty approval, the Des Moines Register reported in December 2014. Worse still, Perlman’s team conducted the MERS research in a biosafety level-2 lab, instead of a level-3 facility as is required by federal regulators, it said.

` The university was also accused of “improperly withholding forms” that would allow the public to assess “whether any of the deadly agent imported from a collaborator in Spain was stolen, lost or released,” according to Des Moines Register.

` Li, who has personally dealt with US experts, told the Global Times that although the US government’s policies in biosecurity seem cautious and mild, a few individual researchers (often with military connections) at front-line labs without foreign technical verification are “innovative, open and audacious,” he said.

` Considering the leading biotechnology posture of US and an intentional ignorance of government departments, Li thinks there is the possibility that individual researchers or teams in the US may have, for example based on its considerable collection of coronavirus strains, secretly modified a virus precursor like COVID-19 without permission. “We can’t simply rule it out.”

` Double standards against China

` In the US, there are lots of biobanks covering a number of industries including agriculture and energy, contributing to a huge sample database that China doesn’t have, said insiders reached by the Global Times.

` No one can guarantee that the US biobanks are 100-percent safe and are subject to effective supervision, they noted.

` With a mixed record on safety, the US’ ambiguous, double-standard attitude toward the COVID-19 lab leak theory has led many in the public to become increasingly suspicious: it keeps smearing Chinese labs for “leaking the virus,” while attempting to cover up its domestic situation.

` Anthony Fauci, a top US expert in public health, was previously criticized by people in and out of the US for being inconsistent on the lab leak theory. Fauci rejected the claim in July, which contradicted his earlier statements such as “not convinced COVID-19 developed naturally” and calling for more investigations focused on Chinese labs.

` Coronavirus expert Baric, whose team reportedly have refuted the lab leak theory though, told Spanish media that some man-made viruses can be “disguised” as coming from nature through techniques, and even implied that files at Wuhan Institute of Virology (WIV) have the answers people want.

` Baric was also among the scientists who jointly wrote a letter in May to criticize the WHO’s investigation into the virus’ origins, which had ruled lab release in Wuhan “extremely unlikely.” “A rigorous investigation would have reviewed the biosafety level under which bat coronavirus research was conducted at WIV,” NBC quoted Baric as saying in June.

` Ironically, while slandering Chinese labs using the lableak claim, the US keeps suppressing the voices that are calling for investigations on its own labs. After Peter Daszak, a British zoologist who had been to Wuhan as a WHO expert team member, condemned The New York Times for engaging in selectively misquoting WHO experts to fit its own narrative, he was defamed by Western media and found his funding cut-off.

` Australian virologist Danielle Anderson, the only foreign scientist to have worked in the high-security BSL-4 lab at the WIV, was threatened by a few extreme conspiracy theorists for defending WIV and refuting the lab leak saying. She had to call the police and lock down running app for safety reasons, Sydney Morning Herald reported in June.

` Western social media platforms also helped to shut down those who raise legitimate questions about US labs, the Global Times found. “Greg Rubini” for example, a Twitter account that US government claimed is owned by a right-wing conspiracy theorist, was suspended after posting tweets that accused the US labs including the ones at the UNC of leaking the COVID-19.

` Driven by the political need to smear and suppress others, the US has been busy muddying the waters, engaged in stigmatization, and turning COVID-19 origins-tracing study into a political weapon, Zhao said on Friday.

` The US “has made lying, vilifying and coercing its standard operating practice without any respect for facts, science or justice,” FM spokesperson Zhao said. “Such despicable behavior will leave a stain in the history of the humanity's fight against diseases.”

`
With records of “lab-created coronaviruses” incidents, supervision loopholes and audacious germ researchers, labs led by Ralph Baric at UNC-Chapel Hill have become focus of public suspicion in the search for virusorigins.
With records of “lab-created coronaviruses” incidents, supervision loopholes and audacious germ researchers, labs led by Ralph Baric at UNC-Chapel Hill have become focus of public suspicion in the search for virusorigins
 
 
 

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llustration: Xu Zihe/Global Times

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VISUAL NEWS

Monday, August 9, 2021

SOPs eased for fully vaccinated, here are the key points

 

PETALING JAYA: Covid-19 restrictions will be eased starting Tuesday (Aug 10) for those who have been fully vaccinated, announces Tan Sri Muhyiddin Yassin.

The Prime Minister said that among the restrictions being lifted were inter-district and interstate travel for long-distance couples, and prayers in houses of worship as well as the ban on dine-ins (for states under Phase Two and above of the National Recovery Plan).

Muhyiddin also said the Covid-19 digital vaccination certification will be used to verify an individual's immunisation status to the authorities.

He explained that individuals would be considered fully vaccinated 14 days after receiving the second dose of either the Pfizer, AstraZeneca or Sinovac vaccines, and 28 days after being jabbed with the single-dose Johnson & Johnson or CanSino vaccines.

Parents who are fully vaccinated will be allowed to travel across borders and states to meet with the children below 18-years-old, he added.

Long-distance married couples who are fully vaccinated will be allowed to travel across districts and states to meet each other, he said.

He said individuals who wanted to travel across borders must show their digital Covid-19 vaccination certificate to enforcement officers manning roadblocks.

At the same time, Muhyiddin also said that for all states, fully-vaccinated Muslims will be allowed to perform solat prayers in mosques and suraus.

Mosque and surau authorities must ensure that SOPs are strictly adhered to at all times and Muslims who come for solat prayers must show their digital Covid-19 vaccination certificate.

He also said the same applies to non-Muslims, where they will be allowed to visit their respective places of worship.

"The implementation of this at non-Muslim places of worship is subjected to the purview of the respective state religious authority and also the National Unity Ministry."

Muhyiddin also advised Malaysians to only dine-in when they need to, and choose premises with good ventilation systems.

"I would also like to propose to food premises operators to prepare more outdoor eating spaces in order to ensure good ventilation.

"We understand that the risks of spreading Covid-19 is high in indoor premises compared to outdoors."

Muhyiddin also said married couples who were fully vaccinated and would like to bring their children below the age of 17 along for dine-ins must strictly abide by the SOPs.

The Prime Minister also said sports without physical contact and recreational activities would be allowed in states under Phase Two of the NRP onwards from 6am to 10pm at outdoor and half-indoor areas.

Dine-ins at restaurants or cafes at clubhouse premises will be also be allowed and customers must show their digital vaccination certificate to verify immunisation status.

However, Muhyiddin said changing rooms and showers at clubhouse premises will not be allowed, in order to avoid groups gathering after sports which could cause the transmission of Covid-19.

The allowed sporting activities include jogging, exercising, taichi, cycling, skateboarding, fishing, equestrian, archery, hiking, singles tennis and badminton and golf, among others.

Meanwhile, Muhyiddin also said tourism activities involving homestays and hotels within the same state will be allowed.

"Homestay and hotel operators must ensure that those patronising their premises must show the digital Covid-19 certification to prove that they are fully vaccinated," he added.

Muhyiddin also said more details would be announced soon by the National Security Council (NSC).

He also said further easing of restrictions on economic sectors were currently being mulled by the government, and an announcement will soon be made.

Muhyiddin stressed that the loosened restrictions did not mean Malaysians can ignore SOPs to curb Covid-19, as there is still a high risk of contracting Covid-19 through dine-ins and sporting activities.

He said he has ordered the relevant ministries and agencies to ensure strict enforcement of SOP compliance in order to avoid Covid-19 infections.

"The government will not hesitate to retract all the loosened restrictions announced if there is non-compliance with the SOPs," he added.

If there were new infections at these premises, Muhyiddin said the Health Ministry will immediately take appropriate action such as risk assessment, which could lead to the closure of the said premises or compound notices to be issued.

Muhyiddin also stressed that Malaysians have a collective responsibility in combating Covid-19.

"The loosened restrictions are proof that the government is confident that Malaysians who received full vaccination doses can make their own risk assessment rationally.

"God-willing, we will win together," he said.

All states are under Phase 2 and beyond of the NRP except for Selangor, Kuala Lumpur, Negri Sembilan, Kedah, Johor, Malacca and Putrajaya.

Muhyiddin also said fully-vaccinated travellers from overseas coming to Malaysia, including Malaysians returning from abroad, will be allowed to self-quarantine at home.

Below is the full speech by the Prime Minister:

FULL TEXT

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US sees 100,000 new cases daily as country faces Delta variant threat while China defeated Delta variant !

 


 Surge in Covid-19 infections and deaths as country faces Delta variant threat


Washington: The US is now averaging 100,000 new Covid-19 infections a day, returning to a milestone last seen during the winter surge in yet another bleak reminder of how quickly the Delta variant has spread through the country.

The US was averaging about 11,000 cases a day in late June. Now the number is 107,143.

It took the US about nine months to cross the 100,000 average case number in November before peaking at about 250,000 in early January.

Cases bottomed out in June but took about six weeks to go back above 100,000, despite a vaccine that has been given to more than 70% of the adult population.

The seven-day average for daily new deaths also increased, according to data from Johns Hopkins University.

It rose over the past two weeks from about 270 deaths per day to nearly 500 a day as of Friday.

The virus is spreading quickly through unvaccinated populations, especially in the South where hospitals have been overrun with patients.

Health officials are fearful that cases will continue to soar if more Americans don’t embrace the vaccine.

“Our models show that if we don’t (vaccinate people), we could be up to several hundred thousand cases a day, similar to our surge in early January,” Centers for Disease Control and Prevention director Rochelle Walensky said on CNN this week.

The number of Americans hospitalised with the virus has also skyrocketed and it has gotten so bad that many hospitals are scrambling to find beds for patients in far-off locations.

Houston officials say the latest wave of Covid-19 cases is pushing the local health care system to nearly “a breaking point”, resulting in some patients having to be transferred out of the city to get medical care, including one who had to be taken to North Dakota.

Dr David Persse, who is health authority for the Houston Health Department and EMS medical director, said some ambulances were waiting hours to offload patients at Houston area hospitals because no beds were available.

Persse said he feared this would lead to prolonged respond times to 911 medical calls.

“The health care system right now is nearly at a breaking point ... For the next three weeks or so, I see no relief on what’s happening in emergency departments,” Persse said Thursday.

Last weekend, a patient in Houston had to be transferred to North Dakota to get medical care.

An 11-month-old girl with Covid19 and who was having seizures had to be transported on Thursday from Houston to a hospital 274km away in Temple, Texas.

In Missouri, 30 ambulances and more than 60 medical personnel will be stationed across the state to help transport Covid-19 patients to other regions if nearby hospitals are too full to admit them, Missouri Governor Mike Parson announced on Friday.- AP
 
 

US averaging 100,000 new COVID-19 infections a day

 

China defeated Delta variant ! China's Success Cannot Be Copied and Pasted


Suppose western countries can recognize Chinese and Indian vaccines and provide enough raw materials to India. In that case, it will be more beneficial to the world than the G7 countries' lip service of delivering 1 billion doses of vaccines to impoverished nations by the end of 2022. 
 
It is noteworthy that the promised donations dropped from 1 billion to 870 million when officially announced in the communique as if lip service also costs something 
 
 

The World's First Inhaled COVID-19 Vaccine Is Coming!

 
  The aerosol inhalation vaccine has similar protective efficacy as the intramuscular vaccine. It has fewer side effects in adults over 18 years of age than the injectable ones. It requires aerosol inhalation only to complete vaccination and obtain triple protection of mucosal immunity, 
 
cellular immunity and humoral immunity. If used as a booster, it can significantly improve the already vaccinated population's multiple immunization effect against the new coronavirus mutation. At the same time, the dose of this vaccine is relatively low, which indirectly increases the yield of the vaccine significantly and can effectively solve the problems of medical waste disposal. As a result, it is more suitable for large-scale vaccination.
 
 
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Saturday, August 7, 2021

The race against Delta; Sinovac Sinopharm discovers potent antibody against Delta variant, effective in early treatment of COVID-19

  Beware of external outbreaks

As cases rise, experts say it’s time to expand Operation Surge Capacity nationwide


With the Delta variant confirmed to be the dominant strain in the country, experts are calling for Malaysia to continue its vaccination drive – especially in states outside the Klang Valley – to outpace the highly-infectious Covid-19 variant.

Greater vaccination efforts are needed in states outside the Klang Valley, health experts say, especially with the Delta variant casting a shadow on the country’s recovery.

With about 98% of the Klang Valley adult population having received at least the first vaccine dose under Operation Surge Capacity, public figures and health experts say attention should now be focused on other states in Malaysia.

“About two months ago, the proportion of cases for Greater Klang Valley represented 60% to 70% of total cases in Malaysia.

“But now it is about 50% to 60%. The rise in cases is both nationally and in Klang Valley, so it’s not just the concern of the Greater Klang Valley but every other state in Malaysia,” said Health deputy director-general (public health) Datuk Dr Chong Chee Kheong.

He added that the strain on the healthcare system in Klang Valley was now more manageable, but other states were now at risk.

International Islamic University Malaysia epidemiologist Prof Dr Jamalludin Ab Rahman suggested roping in community leaders to help get people vaccinated, including manual registration for those without the Mysejahtera app.

“The state government can identify who (the community leaders) are and if they are from rural areas. The government must go to people rather than wait for them to register,” he said.

He said low vaccine registration rates in certain states such as Sabah (44%) and Kelantan (65%) could be due to a lack of knowledge or technology.

“However, we should also study if there are other reasons like misunderstanding about vaccine safety. If that’s the case, the government needs to engage them and educate them,” he said.

Universiti Kebangsaan Malaysia epidemiologist Assoc Prof Dr Azmi Mohd Tamil concurred that lower vaccine sign-up rates in certain states might not necessarily be due to vaccine hesitancy, but to the use of Mysejahtera.

“There are a lot of rural elderly Malays who have yet to register with Mysejahtera,” he said.

“There may be lower IT literacy and lower usage of the Mysejahtera app. Lower broadband or Internet penetration could be a problem too.”

As of Thursday, about 65% of adults in Malaysia have received at least one dose.

However, Sabah still has a relatively low vaccination coverage with about 37% of adults receiving at least one dose, with Kedah and Kelantan showing only slightly higher numbers at 43%.

To ramp up vaccination rates, Medical Practitioners Coalition Association of Malaysia president Dr Raj Kumar Maharajah said doubts that the public might have on the vaccination programme must be addressed.

“There are questions over the efficacy of the vaccines, especially with reports on empty shots and breakthrough infections.

“People are wondering why they need to get vaccinated when people are getting infected. As such, we need public assurance from the government.

“We need to know the vaccination history of the Covid-19 fatalities, or the proportion of vaccinated individuals who went on to Category 4 or 5,” he said.

He added that the government should mobilise the over 7,000 general practitioners (GPS) across the country to aid the vaccination programme.

“The government is not using the GPS to the fullest. They should rope them in, and we must cut down on the number of mega vaccination centres,” he said.

The Star Malaysia by JOSEPH KAOS JR and CLARISSA

 China's vaccine producer Sinopharm discovers potent antibody against Delta variant, effective in early treatment of COVID-19

Photo: VCG 
 
 
  China's vaccine producer Sinopharm announced on Wednesday that the research team discovered a potent neutralizing antibody against the Delta variant that could be effective in short-term preventive and early treatment of COVID-19 triggered by this variant.

The team, led by Yang Xiaoming, Chairman of Sinopharm China National Biotec Group, a Sinopharm subsidiary, found a monoclonal antibody which can effectively block the binding of novel coronavirus to the Angiotensin-converting enzyme 2. This enzyme is attached to the membrane of cells located in the intestines, kidney, testis, gallbladder, and heart and the antibody can prevent the virus from infecting cells, the company announced on its official WeChat account.

Monoclonal antibody, as a targeted therapy drug, has a strong specificity, significant efficacy and low toxicity. Known as the "biological missile", it has shown excellent efficacy and broad application prospects in the treatment of a variety of diseases.

The application of the antibody, called 2B11, can also significantly reduce the pulmonary inflammation caused by virus infection.

The Delta variant has become the main variant in global transmission of COVID-19 and is also the prevailing variant in China. Recent studies showed that 2B11 had a highly consistent neutralization activity against the Delta variant, suggesting that it has great application value in short-term prevention and early treatment of COVID-19 caused by this variant.

The company said the clinical application of the 2B11 antibody is progressing an orderly manner with hopes that it can be used in the prevention and control of COVID-19 in China as soon as possible. The research is expected to be a useful weapon against virus mutation.

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Sinovac to submit application for clinical research and emergency use on vaccines against Gamma and Delta variants in several ountries: company CEO

China's Sinovac will submit an application in several countries for clinical research and emergency use on vaccines targeting the Gamma and Delta variants, Sinovac CEO, Yin Weidong, said on Thursday during a forum on international cooperation on COVID-19 vaccines hosted by Chinese State Councilor and Foreign Minister Wang Yi.


MOH: Too soon to ease restrictions | The Star

 


 

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