The therapeutic properties of exercise is well supported by a substantial amount of research. 
Recent
 studies reported that an increase in the time dedicated to physical 
health-based activities is not associated with a decline in academic 
performance.
THE benefits of exercise are well publicised. Exercise is associated 
with a reduction in physical illnesses such as cardiovascular disease, 
colon and breast cancer, obesity and mental illness (including 
depression and anxiety disorders) across the adult lifespan.
The 
National Health and Morbidity Survey 2011 revealed that about 64.3% of 
Malaysians were physically active. The level of physical activity 
gradually decreased with increasing age, and this was particularly 
apparent in senior citizens.
Despite evidence of the importance 
of exercise, the prevalence of overweight and obese Malaysians was 29.4%
 and 15.1% respectively based on the World Health Organization (1998) 
classification.
Although some are aware of the benefits of 
exercise, there are many who are unaware that exercise has considerable 
benefits for the brain. This is put aptly by John Ratey, author of 
A User’s Guide to the Brain.
“Exercise is really for the brain, not the body. It affects mood, vitality, alertness and feelings of well-being.”
There
 is increasing evidence that exercise can improve learning and memory, 
delay age-related cognitive decline, reduce risk of neurodegeneration 
and alleviate depression.
Exercise and brain function
Exercise
 improves brain function in different ways. It enhances learning and 
plasticity, is neuroprotective, and is therapeutic and protective 
against depression
Exercise enhances learning and plasticity, 
which is the capacity of the brain and nervous system to continuously 
alter neural pathways and synapses in response to experience or injury.
Although
 some are aware of the benefits of exercise, there are many who are 
unaware that exercise has considerable benefits for the brain.
The
 effects of exercise have been demonstrated in ageing human populations 
in which sustained exercise has augmented learning and memory, improved 
executive functions, impeded age-related and disease-related mental 
decline, and protected against age-related atrophy in parts of the brain
 areas that are vital for higher cognitive processes.
Physical 
activity has a positive effect on cognition, which includes every mental
 process that may be described as an experience of knowing (including 
perceiving, recognising, conceiving, and reasoning).
There is a 
significant relationship between physical activity and improved 
cognition in normal adults as well as those with early signs of 
Alzheimer’s disease (AD), in which there is mild impairment of memory or
 cognition.
There is a dose-response relationship between 
exercise and health-related quality of life, with moderate exercise 
associated with the best outcomes.
The literature on the effects 
of exercise on cognition during children’s development is less 
substantial. However, a meta-analysis by Sibley & Etnier reported a 
positive correlation between physical activity and cognitive performance
 in children aged between four and 18 years in eight categories, i.e. 
perceptual skills, intelligence quotient, achievement, verbal tests, 
mathematic tests, memory, developmental level/academic readiness and 
others.
A beneficial relationship was found for all categories, 
with the exception of memory, which was unrelated to physical activity 
behaviour, and for all age groups, although it was stronger for children
 in the ages of four to seven and 11 to 13 years, compared with the ages
 of eight to 10 and 14 to 18 years.
Recent studies have reported 
that an increase in the time dedicated to physical health-based 
activities is not associated with a decline in academic performance.
The
 literature on the impact of exercise on cognition in young adults is 
limited, probably because cognition peaks during young adulthood and 
there is little room for exercise-related improvement at this stage of 
the lifespan.
Although there is considerable evidence that 
exercise can facilitate learning in humans and other animals, there are 
gaps in knowledge regarding the types of learning that are improved with
 exercise.
 Therapeutic exercise programmes after a stroke accelerates functional rehabilitation.
Exercise
 protects the brain (neuroprotective). It reduces the impact of brain 
injury and delays the onset and decline in several neurodegenerative 
diseases. For example, therapeutic exercise programmes after a stroke 
accelerates functional rehabilitation.
Furthermore, physical 
activity delays the onset and reduces the risk for AD, Huntington’s 
disease and Parkinson’s disease, and can even slow functional decline 
after neurodegeneration has begun.
There is evidence that exercise is therapeutic and protective in depression, which is associated with a decline in cognition.
Depression
 is considered to be a health burden that is greater than that of 
ischaemic heart disease, cerebrovascular disease or tuberculosis.
Clinical
 trials have reported the efficacy of aerobic or resistance training 
exercise in the treatment of depression in young and older patients, 
with benefits similar to that of antidepressant medicines. More exercise
 leads to greater improvements.
Trials have also reported 
improvement in depressive symptoms in AD compared to those 
non-exercising individuals whose depressive symptoms worsened.
Bipolar disorders do not appear to respond as well to exercise, but those with anxiety respond even faster.
There
 is a convergence of the concept that brain health and cognition are 
influenced by the interplay of various central and peripheral factors. 
Brain function is believed to be impaired by peripheral risk factors 
that lead to cognitive decline, including hypertension, hyperglycemia, 
insulin insensitivity and dyslipidemia, features that are commonly known
 as the “metabolic syndrome”.
Of these factors, hypertension and 
glucose intolerance play crucial roles. Exercise not only reduces all 
these peripheral risk factors but also improves cardiovascular health, 
lipid–cholesterol balance, energy metabolism, glucose use, insulin 
sensitivity and inflammation.
As such, exercise improves brain 
health and function by directly enhancing brain health and cognitive 
function, and indirectly, by reducing the peripheral risk factors for 
cognitive decline.
It is believed that exercise initiates an 
interactive cascade of growth factor signals which lead to the 
stimulation of plasticity, improvement of cognitive function, reduction 
of the mechanisms that drive depression, stimulation of neurogenesis and
 improvement of cerebrovascular perfusion.
Although much is known
 about the effects of exercise and physical activity on brain and 
cognition, there are many important questions that are unanswered.
They
 include questions like the design of exercise interventions which 
optimise the effects on cognition and brain health; when it is best to 
begin; what are the best varieties, intensities, frequencies and 
duration of exercise; is it ever too late to start an exercise 
programme; and can exercise be used to reduce the effects of 
neurodegenerative diseases.
Knowing the how
Exercise
 affects many sites in the nervous system and stimulates the secretion 
of chemicals like serotonin and dopamine, which make humans feel calm, 
happy, and euphoric. You do not have to wait for these feelings to occur
 – you can initiate them by exercising.
There is no shortage of 
advice on the various physical exercises that enhances cardiovascular 
health. Prior to embarking on exercise, a consultation with the doctor 
would be helpful, especially for senior citizens. This will help in 
choosing the appropriate exercise for one’s individual situation.
In general, what is good for the heart is also good for the brain.
The
 usual recommended minimum is half an hour of moderate exercise thrice a
 week. This can be walking, jogging, swimming, playing games, dancing 
etc.
The public is often reminded about a healthy lifestyle, 
which is focused on physical health. However, it is also important to 
exercise mentally and keep the brain healthy.
There are 
publications and activities available that can help you make a start and
 continue to improve cognition, memory, creativity and other brain 
functions.
Anyone at any age can do so, even senior citizens. It is moot to remember the adage: if you don’t use it, you lose it.
Malaysia Festival of the Mind 2013
The
 ninth Malaysia Festival of the Mind will be held from June 15-16, 2013,
 at Universiti Tunku Abdul Rahman (UTAR) Perak Campus in Kampar, and 
June 22-23 at Tunku Abdul Rahman University College (TARC) Main Campus 
in Setapak, Kuala Lumpur.
It is open to the public from 9.30am - 
4.30pm. Talks, workshops, exhibitions and competitions will be held to 
create awareness about the human mind and its unlimited potential; as 
well as ways of tapping into and developing one’s brainpower to the 
fullest.
For further information, visit 
www.utar.edu.my/mmlm or email 
mmlm@utar.edu.my or call (03) 7625 0328 (Justin/Sin Yee) or (05) 468 8888 (Wei See/Jamaliah).
By Dr MILTON LUM
> 
Dr
 Milton Lum is a member of the board of Medical Defence Malaysia. This 
article is not intended to replace, dictate or define evaluation by a 
qualified doctor. The views expressed do not represent that of any 
organisation the writer is associated with. For further information, 
e-mail starhealth@thestar.com.my.
 The information provided is for educational and communication purposes 
only and it should not be construed as personal medical advice. 
Information published in this article is not intended to replace, 
supplant or augment a consultation with a health professional regarding 
the reader’s own medical care. The Star does not give any warranty on 
accuracy, completeness, functionality, usefulness or other assurances as
 to the content appearing in this column. The Star disclaims all 
responsibility for any losses, damage to property or personal injury 
suffered directly or indirectly from reliance on such information.
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